JVM-13
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Description
Description: Derived from the peripheral blood of a human Caucasian male patient with prolymphocytic leukaemia. Cells have been subsequently transformed by treatment with EBV and TPA (12-0-tetradecanoylphorbol-13-acetate). JVM-13 cells express surface-membrane and cytoplasmic lambda light chain immunoglobulin. Immunological markers detected were HLA-DR, CD19, CD20, CD21, FMC7, CD38, CD71 and CD9.
Also Known As:
Species: Human
Tissue: blood
Growth Properties: Suspension
Morphology: Lymphoblastoid
Growth Medium: RPMI 1640 + 4mM Glutamine + 10% Foetal Bovine Serum (FBS).
Subculturing Procedure: Maintain cultures between 3-9×100,000 cells/ml; 5% CO2; 37°C.
Release Conditions: No
Depositor: Dr J V Melo, Department of Haematology, RPMS, Hammersmith Hospital, London
Originator: Yes
References: Clin Exp Immunol 1988;73:23
Hyperlink to ECACC Cell Line Data Sheet: 96090516
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